AMPK is an enzyme that is fully known as Adenosine Monophosphate-Activated Protein Kinase. This enzyme is found in every cell of the living body. It serves as a regulator switch to promote cell growth, metabolism, and revitalize aging cells and inhibit the damaging factors in the body that result in aging. It is therefore known as the 'youthful' enzyme. AMPK activation can protect our bodies against cancers and other neurodegenerative diseases. This is because its activation can protect cell damage that comes as a result of oxidative stress. It, therefore, prevents the initiation of cancer and tumor cells. People who are obese can activate AMPK in cells of the liver, fat, and muscles. Exercise is one of the natural AMPK activators that can, therefore, lead to loss of fat and consequently improve muscle performance.
It is also important to note that reducing the amount of calorie intake activates AMPK. Scientists have proven that those who take high levels of glucose and excess saturated fat inhibit stimulation of the enzyme AMPK. This, in turn, leads to cancer progression, aging, and diabetes. When someone is exposed to cold, the AMPK enzyme in the body is activated. Some drugs are said to act as AMPK Activators for weight loss. Metformin is an example of a drug that activates AMPK due to its anti-diabetic functions. Metformin is a blood sugar reducing agent that stimulates fat metabolism as well as glucose intake in the cells.
Thiazolidinedione is an anti-diabetic drug that is also known to activate AMPK enzyme. This drug controls blood sugar which in turn is important for stimulation of AMPK. Adiponectin is a hormonal enzyme produced by fat cells to signal for food deprivation in the body. This enzyme is produced when one is fasting. It stimulates AMPK which in turn results in induced food intake and decreased use of energy. Leptin is also a hormone that is produced to reduce cravings for snacks and sugar consumption. It prevents AMPK in the hypothalamus from suppressing appetite. In so doing, it helps to prevent overeating. This hormone also activates AMPK in the muscles. Check out this website at http://psychology.wikia.com/wiki/Weight_loss for more facts about weight loss.
AMPKActivatoris very important in the body for various reasons. Apart from the statement as mentioned earlier about reducing aging n cells, it also promotes autophagy. Autophagy is the process of renewing cell organelles as well as degrading damaged or misfolded cellular components in the body cells, thus stimulating mitochondrial metabolism by the provision of enough energy. Activation of AMPK is also known to increase production of hormonal sex gamete cells which in turn acts as a boost for fertility. It is about time you check your diet so that you may facilitate the action of AMPK enzyme in your body cells.